Grandparent scam: London, Ont., senior beats fraudsters not once, but twice
It was a typical Tuesday for Mabel Beharrell, 84, until she got the call that would turn her world upside down. Her teenaged grandson was in trouble and needed her help.
The U.S. health regulator authorized a lower dose of Regeneron Pharmaceutical's COVID-19 antibody cocktail that can be given by injection, a move that could ease logistical challenges stemming from administering a higher dose intravenously.
The therapy, REGEN-COV, and a similar treatment developed by rival Eli Lilly were being given through one-time infusion and required patients to be isolated.
Regeneron had been working on a lower dose of its cocktail that can be given subcutaneously to address the challenges that have weighed on demand for antibody drugs.
The U.S. Food and Drug Administration had in November authorized a 2,400 mg dose of REGEN-COV, administered as a single dose directly injected to a vein for non-hospitalized COVID-19 patients.
The agency has now lowered it to 1,200 mg and allowed the administration of casirivimab and imdevimab by injecting under the skin when intravenous infusion is not possible and would lead to treatment delay, Regeneron said on Friday.
The therapy belongs to a class of drugs called monoclonal antibodies, which mimic natural antibodies the body produces to fight off the infection.
Eli Lilly's antibody combination received U.S. emergency use authorization in February, while an antibody drug by Vir Biotechnology Inc and GlaxoSmithKline PLC, which is also administered through intravenous infusion, was granted authorization late last month.
Regeneron said it expects to submit an application for full approval of REGEN-COV in non-hospitalized patients later this summer.
The drugmaker expects to deliver at least 1 million doses of the therapy to the U.S. government in the second quarter and said the government may accept additional doses of up to 1.25 million doses through September.
Regeneron is also developing the cocktail as a preventive medicine.
(Reporting by Manojna Maddipatla and Amruta Khandekar in Bengaluru; Editing by Arun Koyyur)
It was a typical Tuesday for Mabel Beharrell, 84, until she got the call that would turn her world upside down. Her teenaged grandson was in trouble and needed her help.
The deaths of four people on a farm near the Saskatchewan village of Neudorf have been confirmed a murder-suicide.
The Canada Revenue Agency announced Thursday it will not require 'bare trust' reporting from Canadians that it introduced for the 2024 tax season, just four days before the April 2 deadline.
The Parole Board of Canada has granted full parole to one of three men convicted in the brutal murders of three McDonald's restaurant workers in Cape Breton more than 30 years ago.
Nearly 20 hours after a man climbed and remained perched on top of the Reconciliation Bridge in downtown Calgary, the situation came to a peaceful resolution.
Ontario released its annual sunshine list Thursday afternoon, noting that the largest year-over-year increases were in hospitals, municipalities, and post-secondary sectors.
Genetic analysis has shed light on a long-standing mystery surrounding the fates of U.S. President George Washington's younger brother Samuel and his kin.
A spokesman for a regional Muslim advocacy group says Conservative Leader Pierre Poilievre's stance on the Israel-Hamas war could complicate his party's relationship with Muslim Canadians.
Former U.S. President Donald Trump is officially selling a copy of the Bible themed to Lee Greenwood’s famous song, 'God Bless the USA.' But the concept of a Bible covered in the American flag has raised concern among religious circles.
B.C. conservation officers recently seized a nine-foot-long Burmese python from a home in Chilliwack.
A New Brunswicker will go to bed Thursday night much richer than he was Wednesday after collecting on a winning lottery ticket he let sit on his bedroom dresser for nearly a year.
The Ontario government is introducing changes to auto-insurance, but some experts say the move is ill-advised.
A Toronto restaurant introduced a surprising new rule that reduced the cost of a meal and raised the salaries of staff.
Newfoundland’s unique version of the Pine Marten has grown out of its threatened designation.
A Toronto man is out $12,000 after falling victim to a deepfake cryptocurrency scam that appeared to involve Prime Minister Justin Trudeau.
It started small with a little pop tab collection to simply raise some money for charity and help someone — but it didn’t take long for word to get out that 10-year-old Jace Weber from Mildmay, Ont. was quickly building up a large supply of aluminum pop tabs.
There’s a group of people in Saskatoon that proudly call themselves dumpster divers, and they’re turning the city’s trash into treasure.
Ontario is facing a larger than anticipated deficit but the Doug Ford government still plans to balance its books before the next provincial election.