My Bibliography

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Huang TY, Chen LC, Li XP, Li WH, Xu SX, Nagy C, Ibrahim P, Nie ZW, Yang NY, Zeng L, Huang HW, Turecki G, Xie XH. Elevated triglycerides and low triiodothyronine: Key risk factors for coronary artery calcification in patients with schizophrenia. Schizophr Res. 2024 Feb;264:113-121. doi: 10.1016/j.schres.2023.12.007. Epub 2023 Dec 20. PubMed PMID: 38128342.

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Xie XH, Xu SX, Yao L, Chen MM, Zhang H, Wang C, Nagy C, Liu Z. Altered in vivo early neurogenesis traits in patients with depression: Evidence from neuron-derived extracellular vesicles and electroconvulsive therapy. Brain Stimul. 2024 Jan-Feb;17(1):19-28. doi: 10.1016/j.brs.2023.12.006. Epub 2023 Dec 13. PubMed PMID: 38101468.

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Barde S, Aguila J, Zhong W, Solarz A, Mei I, Prud'homme J, Palkovits M, Turecki G, Mulder J, Uhlén M, Nagy C, Mechawar N, Hedlund E, Hökfelt T. Substance P, NPY, CCK and their receptors in five brain regions in major depressive disorder with transcriptomic analysis of locus coeruleus neurons. Eur Neuropsychopharmacol. 2024 Jan;78:54-63. doi: 10.1016/j.euroneuro.2023.09.004. Epub 2023 Nov 4. PubMed PMID: 37931511.

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Morgunova A, Ibrahim P, Chen GG, Coury SM, Turecki G, Meaney MJ, Gifuni A, Gotlib IH, Nagy C, Ho TC, Flores C. Preparation and processing of dried blood spots for microRNA sequencing. Biol Methods Protoc. 2023;8(1):bpad020. doi: 10.1093/biomethods/bpad020. eCollection 2023. Review. PubMed PMID: 37901452; PubMed Central PMCID: PMC10603595.

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Fitzgerald E, Arcego DM, Shen MJ, O'Toole N, Wen X, Nagy C, Mostafavi S, Craig K, Silveira PP, Rayan NA, Diorio J, Meaney MJ, Zhang TY. Sex and cell-specific gene expression in corticolimbic brain regions associated with psychiatric disorders revealed by bulk and single-nuclei RNA sequencing. EBioMedicine. 2023 Sep;95:104749. doi: 10.1016/j.ebiom.2023.104749. Epub 2023 Aug 5. PubMed PMID: 37549631; PubMed Central PMCID: PMC10432187.

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Wu J, Li Y, Huang Y, Liu L, Zhang H, Nagy C, Tan X, Cheng K, Liu Y, Pu J, Wang H, Wu Q, Perry SW, Turecki G, Wong ML, Licinio J, Zheng P, Xie P. Integrating spatial and single-nucleus transcriptomic data elucidates microglial-specific responses in female cynomolgus macaques with depressive-like behaviors. Nat Neurosci. 2023 Aug;26(8):1352-1364. doi: 10.1038/s41593-023-01379-4. Epub 2023 Jul 13. PubMed PMID: 37443281.

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Lin R, Kos A, Lopez JP, Dine J, Fiori LM, Yang J, Ben-Efraim Y, Aouabed Z, Ibrahim P, Mitsuhashi H, Wong TP, Ibrahim EC, Belzung C, Blier P, Farzan F, Frey BN, Lam RW, Milev R, Muller DJ, Parikh SV, Soares C, Uher R, Nagy C, Mechawar N, Foster JA, Kennedy SH, Chen A, Turecki G. SNORD90 induces glutamatergic signaling following treatment with monoaminergic antidepressants. Elife. 2023 Jul 11;12. doi: 10.7554/eLife.85316. PubMed PMID: 37432876; PubMed Central PMCID: PMC10335830.

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Khoury R, Nagy C. Running from stress: a perspective on the potential benefits of exercise-induced small extracellular vesicles for individuals with major depressive disorder. Front Mol Biosci. 2023;10:1154872. doi: 10.3389/fmolb.2023.1154872. eCollection 2023. Review. PubMed PMID: 37398548; PubMed Central PMCID: PMC10309045.

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Maitra M, Mitsuhashi H, Rahimian R, Chawla A, Yang J, Fiori LM, Davoli MA, Perlman K, Aouabed Z, Mash DC, Suderman M, Mechawar N, Turecki G, Nagy C. Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes. Nat Commun. 2023 May 22;14(1):2912. doi: 10.1038/s41467-023-38530-5. PubMed PMID: 37217515; PubMed Central PMCID: PMC10203145.

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Fuh SC, Fiori LM, Turecki G, Nagy C, Li Y. Multi-omic modeling of antidepressant response implicates dynamic immune and inflammatory changes in individuals who respond to treatment. PLoS One. 2023;18(5):e0285123. doi: 10.1371/journal.pone.0285123. eCollection 2023. PubMed PMID: 37186582; PubMed Central PMCID: PMC10184917.

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Matosin N, Arloth J, Czamara D, Edmond KZ, Maitra M, Fröhlich AS, Martinelli S, Kaul D, Bartlett R, Curry AR, Gassen NC, Hafner K, Müller NS, Worf K, Rehawi G, Nagy C, Halldorsdottir T, Cruceanu C, Gagliardi M, Gerstner N, Ködel M, Murek V, Ziller MJ, Scarr E, Tao R, Jaffe AE, Arzberger T, Falkai P, Kleinmann JE, Weinberger DR, Mechawar N, Schmitt A, Dean B, Turecki G, Hyde TM, Binder EB. Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. Acta Neuropathol. 2023 Apr;145(4):439-459. doi: 10.1007/s00401-023-02541-9. Epub 2023 Feb 2. PubMed PMID: 36729133; PubMed Central PMCID: PMC10020280.

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Mitsuhashi H, Nagy C. Potential Roles of m6A and FTO in Synaptic Connectivity and Major Depressive Disorder. Int J Mol Sci. 2023 Mar 25;24(7). doi: 10.3390/ijms24076220. Review. PubMed PMID: 37047192; PubMed Central PMCID: PMC10093820.

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Tanti A, Belliveau C, Nagy C, Maitra M, Denux F, Perlman K, Chen F, Mpai R, Canonne C, Théberge S, McFarquhar A, Davoli MA, Belzung C, Turecki G, Mechawar N. Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: a possible implication of oligodendrocyte progenitor cells. Mol Psychiatry. 2022 Mar;27(3):1552-1561. doi: 10.1038/s41380-021-01372-y. Epub 2021 Nov 19. PubMed PMID: 34799691; PubMed Central PMCID: PMC9095471.

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Ponton E, Turecki G, Nagy C. Sex Differences in the Behavioral, Molecular, and Structural Effects of Ketamine Treatment in Depression. Int J Neuropsychopharmacol. 2022 Jan 12;25(1):75-84. doi: 10.1093/ijnp/pyab082. Review. PubMed PMID: 34894233; PubMed Central PMCID: PMC8756094.

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Romero-Pimentel AL, Almeida D, Muñoz-Montero S, Rangel C, Mendoza-Morales R, Gonzalez-Saenz EE, Nagy C, Chen G, Aouabed Z, Theroux JF, Turecki G, Martinez-Levy G, Walss-Bass C, Monroy-Jaramillo N, Fernández-Figueroa EA, Gómez-Cotero A, García-Dolores F, Morales-Marin ME, Nicolini H. Integrative DNA Methylation and Gene Expression Analysis in the Prefrontal Cortex of Mexicans Who Died by Suicide. Int J Neuropsychopharmacol. 2021 Dec 8;24(12):935-947. doi: 10.1093/ijnp/pyab042. PubMed PMID: 34214149; PubMed Central PMCID: PMC8653872.

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Saeedi S, Nagy C, Ibrahim P, Théroux JF, Wakid M, Fiori LM, Yang J, Rotzinger S, Foster JA, Mechawar N, Kennedy SH, Turecki G. Neuron-derived extracellular vesicles enriched from plasma show altered size and miRNA cargo as a function of antidepressant drug response. Mol Psychiatry. 2021 Dec;26(12):7417-7424. doi: 10.1038/s41380-021-01255-2. Epub 2021 Aug 12. PubMed PMID: 34385599.

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Ibrahim P, Almeida D, Nagy C, Turecki G. Molecular impacts of childhood abuse on the human brain. Neurobiol Stress. 2021 Nov;15:100343. doi: 10.1016/j.ynstr.2021.100343. eCollection 2021 Nov. Review. PubMed PMID: 34141833; PubMed Central PMCID: PMC8187840.

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Vaillancourt K, Chen GG, Fiori L, Maussion G, Yerko V, Théroux JF, Ernst C, Labonté B, Calipari E, Nestler EJ, Nagy C, Mechawar N, Mash DC, Turecki G. Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum. iScience. 2021 Oct 22;24(10):103169. doi: 10.1016/j.isci.2021.103169. eCollection 2021 Oct 22. PubMed PMID: 34693223; PubMed Central PMCID: PMC8517202.

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Fiori LM, Orri M, Aouabed Z, Théroux JF, Lin R, Nagy C, Frey BN, Lam RW, MacQueen GM, Milev R, Müller DJ, Parikh SV, Rotzinger S, Uher R, Foster JA, Kennedy SH, Turecki G. Treatment-emergent and trajectory-based peripheral gene expression markers of antidepressant response. Transl Psychiatry. 2021 Aug 21;11(1):439. doi: 10.1038/s41398-021-01564-8. PubMed PMID: 34420030; PubMed Central PMCID: PMC8380246.

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Chawla A, Nagy C, Turecki G. Chromatin Profiling Techniques: Exploring the Chromatin Environment and Its Contributions to Complex Traits. Int J Mol Sci. 2021 Jul 16;22(14). doi: 10.3390/ijms22147612. Review. PubMed PMID: 34299232; PubMed Central PMCID: PMC8305586.

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Vaillancourt K, Yang J, Chen GG, Yerko V, Théroux JF, Aouabed Z, Lopez A, Thibeault KC, Calipari ES, Labonté B, Mechawar N, Ernst C, Nagy C, Forné T, Nestler EJ, Mash DC, Turecki G. Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster. Mol Psychiatry. 2021 Jul;26(7):3134-3151. doi: 10.1038/s41380-020-00909-x. Epub 2020 Oct 12. PubMed PMID: 33046833; PubMed Central PMCID: PMC8039060.

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Bahrami M, Maitra M, Nagy C, Turecki G, Rabiee HR, Li Y. Deep feature extraction of single-cell transcriptomes by generative adversarial network. Bioinformatics. 2021 Jun 16;37(10):1345-1351. doi: 10.1093/bioinformatics/btaa976. PubMed PMID: 33226074.

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Maitra M, Nagy C, Chawla A, Wang YC, Nascimento C, Suderman M, Théroux JF, Mechawar N, Ragoussis J, Turecki G. Extraction of nuclei from archived postmortem tissues for single-nucleus sequencing applications. Nat Protoc. 2021 Jun;16(6):2788-2801. doi: 10.1038/s41596-021-00514-4. Epub 2021 May 10. PubMed PMID: 33972803.

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Lecompte V, Robins S, King L, Solomonova E, Khan N, Moss E, Nagy C, Feeley N, Gold I, Hayton B, Turecki G, Zelkowitz P. Examining the role of mother-child interactions and DNA methylation of the oxytocin receptor gene in understanding child controlling attachment behaviors. Attach Hum Dev. 2021 Feb;23(1):37-55. doi: 10.1080/14616734.2019.1708422. Epub 2020 Jan 3. PubMed PMID: 31900042.

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Matosin N, Arloth J, Martinelli S, Czamara D, Maitra M, Halldorsdottir T, Cruceanu C, Kaul D, Gassen N, Hafner K. Genotype and age influence cortical-FKBP5 at multiple regulatory and single-cell-type levels in severe psychiatric disorders. bioRxiv. 2021.

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Nagy C, Maitra M, Tanti A, Suderman M, Théroux JF, Davoli MA, Perlman K, Yerko V, Wang YC, Tripathy SJ, Pavlidis P, Mechawar N, Ragoussis J, Turecki G. Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons. Nat Neurosci. 2020 Jun;23(6):771-781. doi: 10.1038/s41593-020-0621-y. Epub 2020 Apr 27. PubMed PMID: 32341540.

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MacKinnon AL, Feeley N, Gold I, Hayton B, King L, Nagy C, Robins S, Turecki G, Zelkowitz P. The interaction between oxytocin receptor gene methylation and maternal behavior on children's early theory of mind abilities. Dev Psychopathol. 2020 May;32(2):511-519. doi: 10.1017/S0954579419000257. PubMed PMID: 31030686.

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Belzeaux R, Gorgievski V, Fiori LM, Lopez JP, Grenier J, Lin R, Nagy C, Ibrahim EC, Gascon E, Courtet P, Richard-Devantoy S, Berlim M, Chachamovich E, Théroux JF, Dumas S, Giros B, Rotzinger S, Soares CN, Foster JA, Mechawar N, Tall GG, Tzavara ET, Kennedy SH, Turecki G. GPR56/ADGRG1 is associated with response to antidepressant treatment. Nat Commun. 2020 Apr 2;11(1):1635. doi: 10.1038/s41467-020-15423-5. PubMed PMID: 32242018; PubMed Central PMCID: PMC7118175.

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Jessa S, Blanchet-Cohen A, Krug B, Vladoiu M, Coutelier M, Faury D, Poreau B, De Jay N, Hébert S, Monlong J, Farmer WT, Donovan LK, Hu Y, McConechy MK, Cavalli FMG, Mikael LG, Ellezam B, Richer M, Allaire A, Weil AG, Atkinson J, Farmer JP, Dudley RWR, Larouche V, Crevier L, Albrecht S, Filbin MG, Sartelet H, Lutz PE, Nagy C, Turecki G, Costantino S, Dirks PB, Murai KK, Bourque G, Ragoussis J, Garzia L, Taylor MD, Jabado N, Kleinman CL. Stalled developmental programs at the root of pediatric brain tumors. Nat Genet. 2019 Dec;51(12):1702-1713. doi: 10.1038/s41588-019-0531-7. Epub 2019 Nov 25. PubMed PMID: 31768071; PubMed Central PMCID: PMC6885128.

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Solomonova E, Lee YEA, Robins S, King L, Feeley N, Gold I, Hayton B, Libman E, Nagy C, Turecki G, Zelkowitz P. Sleep quality is associated with vasopressin methylation in pregnant and postpartum women with a history of psychosocial stress. Psychoneuroendocrinology. 2019 Sep;107:160-168. doi: 10.1016/j.psyneuen.2019.05.010. Epub 2019 May 10. PubMed PMID: 31132568.

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Duffy A, Goodday SM, Keown-Stoneman C, Scotti M, Maitra M, Nagy C, Horrocks J, Turecki G. Epigenetic markers in inflammation-related genes associated with mood disorder: a cross-sectional and longitudinal study in high-risk offspring of bipolar parents. Int J Bipolar Disord. 2019 Aug 6;7(1):17. doi: 10.1186/s40345-019-0152-1. PubMed PMID: 31385059; PubMed Central PMCID: PMC6682840.

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Saeedi S, Israel S, Nagy C, Turecki G. The emerging role of exosomes in mental disorders. Transl Psychiatry. 2019 Mar 28;9(1):122. doi: 10.1038/s41398-019-0459-9. Review. PubMed PMID: 30923321; PubMed Central PMCID: PMC6438960.

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Maitra M, Nagy C, Turecki G. Sequencing the human brain at single-cell resolution. Current Behavioral Neuroscience Reports. 2019; 6(4):197-208.

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Nagy C, Vaillancourt K, Turecki G. A role for activity-dependent epigenetics in the development and treatment of major depressive disorder. Genes Brain Behav. 2018 Mar;17(3):e12446. doi: 10.1111/gbb.12446. Epub 2018 Jan 9. Review. PubMed PMID: 29251832.

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King L, Robins S, Chen G, Yerko V, Zhou Y, Nagy C, Feeley N, Gold I, Hayton B, Turecki G, Zelkowitz P. Perinatal depression and DNA methylation of oxytocin-related genes: a study of mothers and their children. Horm Behav. 2017 Nov;96:84-94. doi: 10.1016/j.yhbeh.2017.09.006. Epub 2017 Sep 19. PubMed PMID: 28918249.

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Nagy C, Torres-Platas SG, Mechawar N, Turecki G. Repression of Astrocytic Connexins in Cortical and Subcortical Brain Regions and Prefrontal Enrichment of H3K9me3 in Depression and Suicide. Int J Neuropsychopharmacol. 2017 Jan 1;20(1):50-57. doi: 10.1093/ijnp/pyw071. PubMed PMID: 27516431; PubMed Central PMCID: PMC5737582.

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Nagy C. Epigenetic Regulation of Astrocytic Dysfunction in Depression and Suicide. McGill University Libraries; 2017.

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Cruceanu C, Kutsarova E, Chen ES, Checknita DR, Nagy C, Lopez JP, Alda M, Rouleau GA, Turecki G. DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression. BMC Psychiatry. 2016 Aug 11;16(1):286. doi: 10.1186/s12888-016-0989-0. PubMed PMID: 27515700; PubMed Central PMCID: PMC4982122.

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Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G. Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval. Front Genet. 2016;7:120. doi: 10.3389/fgene.2016.00120. eCollection 2016. PubMed PMID: 27446202; PubMed Central PMCID: PMC4917525.

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Torres-Platas SG, Nagy C, Wakid M, Turecki G, Mechawar N. Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides. Mol Psychiatry. 2016 Apr;21(4):509-15. doi: 10.1038/mp.2015.65. Epub 2015 Jun 2. PubMed PMID: 26033239.

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Nagy C, Turecki G. Transgenerational epigenetic inheritance: an open discussion. Epigenomics. 2015 Aug;7(5):781-90. doi: 10.2217/epi.15.46. Epub 2015 Sep 7. Review. PubMed PMID: 26344807.

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Nagy C, Maheu M, Lopez JP, Vaillancourt K, Cruceanu C, Gross JA, Arnovitz M, Mechawar N, Turecki G. Effects of postmortem interval on biomolecule integrity in the brain. J Neuropathol Exp Neurol. 2015 May;74(5):459-69. doi: 10.1097/NEN.0000000000000190. PubMed PMID: 25868148.

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Nagy C, Suderman M, Yang J, Szyf M, Mechawar N, Ernst C, Turecki G. Astrocytic abnormalities and global DNA methylation patterns in depression and suicide. Mol Psychiatry. 2015 Mar;20(3):320-8. doi: 10.1038/mp.2014.21. Epub 2014 Mar 25. PubMed PMID: 24662927; PubMed Central PMCID: PMC5293540.

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Maussion G, Yang J, Suderman M, Diallo A, Nagy C, Arnovitz M, Mechawar N, Turecki G. Functional DNA methylation in a transcript specific 3'UTR region of TrkB associates with suicide. Epigenetics. 2014 Aug;9(8):1061-70. doi: 10.4161/epi.29068. Epub 2014 May 6. PubMed PMID: 24802768; PubMed Central PMCID: PMC4164491.

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Chen GG, Diallo AB, Poujol R, Nagy C, Staffa A, Vaillancourt K, Lutz PE, Ota VK, Mash DC, Turecki G, Ernst C. BisQC: an operational pipeline for multiplexed bisulfite sequencing. BMC Genomics. 2014 Apr 16;15:290. doi: 10.1186/1471-2164-15-290. PubMed PMID: 24734894; PubMed Central PMCID: PMC4234473.

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Cruceanu C, Alda M, Nagy C, Freemantle E, Rouleau GA, Turecki G. H3K4 tri-methylation in synapsin genes leads to different expression patterns in bipolar disorder and major depression. Int J Neuropsychopharmacol. 2013 Mar;16(2):289-99. doi: 10.1017/S1461145712000363. Epub 2012 May 9. PubMed PMID: 22571925; PubMed Central PMCID: PMC3564952.

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Nagy C, Turecki G. Sensitive periods in epigenetics: bringing us closer to complex behavioral phenotypes. Epigenomics. 2012 Aug;4(4):445-57. doi: 10.2217/epi.12.37. Review. PubMed PMID: 22920183; PubMed Central PMCID: PMC5293543.

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Ernst C, Nagy C, Kim S, Yang JP, Deng X, Hellstrom IC, Choi KH, Gershenfeld H, Meaney MJ, Turecki G. Dysfunction of astrocyte connexins 30 and 43 in dorsal lateral prefrontal cortex of suicide completers. Biol Psychiatry. 2011 Aug 15;70(4):312-9. doi: 10.1016/j.biopsych.2011.03.038. Epub 2011 May 14. PubMed PMID: 21571253.